Friday, July 6, 2018

BRCA1 and BRCA2 genetic mutations

Most inherited cases of breast cancer are associated with mutations in two genes:
 BRCA1 (BReast CAncer gene one) and  
BRCA2 (BReast CAncer gene two).

Everyone has #BRCA1 and #BRCA2 genes. The function of the #BRCA genes is to repair cell damage and keep breast, ovarian, and other cells growing normally. But when these genes contain mutations that are passed from generation to generation, the genes don't function normally and breast, ovarian, and other cancer risk increases. BRCA1 and BRCA2 mutations may account for up to 10% of all breast cancers, or 1 out of every 10 cases.
Having a BRCA1 or BRCA2 mutation doesn't mean you will be diagnosed with breast cancer. Researchers are learning that other mutations in pieces of chromosomes -- called SNPs (single nucleotide polymorphisms) -- may be linked to higher breast cancer risk in women with a BRCA1 mutation as well as women who didn't inherit a breast cancer gene mutation.

Women who are diagnosed with breast cancer and have a BRCA1 or BRCA2 mutation often have a family history of breast cancer, ovarian cancer, and other cancers. Still, most people who develop breast cancer did not inherit a genetic mutation linked to breast cancer and have no family history of the disease. 

Join with us at #Breast_Cancer2018_conference on #October15-16,2018 at #Rome, Italy.  
 follow the link for more details-https://bit.ly/2s8xD6O 
submit an #Abstract on-https://bit.ly/2IaExiN 
Alternatively mail your query at- breastcancer@pulsusevents.org /breastcancer@pulsusmeet.org

1 comment:

  1. Very informative blog. This blog share complete information on BRCA1 and BRCA2 genes mutations. I found this information very helpful. Thanks for sharing

    ReplyDelete

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